{"product_id":"recombinant-human-cd300a-lmir1-protein-fc-his-tag-pksh032700","title":"Recombinant Human CD300a\/LMIR1 Protein (Fc \u0026 His Tag) - PKSH032700","description":"\u003cp\u003eRecombinant Human CD300a\/LMIR1 Protein (Fc \u0026amp; His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032700-10, PKSH032700-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD300a; LMIR1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CMRF35-Like Molecule 8; CLM-8; CD300 Antigen-Like Family Member A; CMRF-35-H9; CMRF35-H9; CMRF35-H; IRC1\/IRC2; Immunoglobulin Superfamily Member 12; IgSF12; Inhibitory Receptor Protein 60; IRp60; NK Inhibitory Receptor; CD300a; CD300A; CMRF35H; IGSF12\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UGN4\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9UGN4\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b; CD300e) and inhibitory members (CD300a; CD300f); as well as molecules presenting a negative charge within their transmembrane domain (CD300c; CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu18-Gln178\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris; 150mM NACl; 5% Trehalose; pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 45.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 75 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068878618803,"sku":"PKSH032700-10","price":163.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068878651571,"sku":"PKSH032700-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_92dc8837-b6b4-4b44-913e-e406c7089b15.png?v=1708598476","url":"https:\/\/afsbio.com\/products\/recombinant-human-cd300a-lmir1-protein-fc-his-tag-pksh032700","provider":"AFSBio Inc.","version":"1.0","type":"link"}