{"product_id":"recombinant-human-cd38-protein-his-tag-pksh033780","title":"Recombinant Human CD38 Protein (His Tag) - PKSH033780","description":"\u003cp\u003eRecombinant Human CD38 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033780-10, PKSH033780-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD38\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: ADP-ribosyl cyclase\/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule; CD38\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cancer; immunology; metabolism; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P28907\u003c\/p\u003e\n\n\u003cp\u003eAccession: P28907\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD38; also known as ADP-ribosyl cyclase\/cyclic ADP-ribose hydrolase 1; is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas; liver; kidney; brain; testis; ovary; placenta; malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate; the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Val43-Ile300\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 30.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38-50 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113990521011,"sku":"PKSH033780-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113990553779,"sku":"PKSH033780-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b6951939-ff0a-483a-b563-a61c7391d02e.png?v=1709549811","url":"https:\/\/afsbio.com\/products\/recombinant-human-cd38-protein-his-tag-pksh033780","provider":"AFSBio Inc.","version":"1.0","type":"link"}