{"product_id":"recombinant-human-cd38-protein-rp00151","title":"Recombinant Human CD38 Protein - RP00151","description":"\u003cp\u003eRecombinant Human CD38 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00151-10, RP00151-20, RP00151-50, RP00151-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human CD38 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val43-Ile300) of human CD38 (Accession #NP_001766.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CD38, ADPRC 1, ADPRC1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P28907\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 952\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE; ≥95 % as determined by HPLC.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: 1.Measured by its binding ability in a functional ELISA. Immobilized Human CD38 Protein at 1μg\/mL (100 μL\/well) can bind CD38 Rabbit pAb with a linear range of 0.244-3.2 ng\/mL.|2.Loaded CD38 Rabbit mAb (Catalog:A20215) on ProA Biosensor, can bind Human CD38 Protein, C-His (Catalog: RP00151) with an affinity constant of 4.1 nM as determined in BLI assay (Gator).\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: VPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198296940723,"sku":"RP00151-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198296973491,"sku":"RP00151-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198297006259,"sku":"RP00151-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198297039027,"sku":"RP00151-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_21f3e100-e75c-4c52-b47f-d42e1fa2d720.png?v=1766960273","url":"https:\/\/afsbio.com\/products\/recombinant-human-cd38-protein-rp00151","provider":"AFSBio Inc.","version":"1.0","type":"link"}