{"product_id":"recombinant-human-cd52-c-fc-avi-biotinylated-pksh033863","title":"Recombinant Human CD52 (C-Fc-Avi) Biotinylated - PKSH033863","description":"\u003cp\u003eRecombinant Human CD52 (C-Fc-Avi) Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033863-20, PKSH033863-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD52\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: CAMPATH-1 antigen; CAMPATH-1; CD52 antigen; CD52 molecule; CD52; CDw52; Epididymal secretory protein E5; He5; HEL-S-171mP; Human epididymis-specific protein 5\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc-Avi\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P31358\u003c\/p\u003e\n\n\u003cp\u003eAccession: P31358\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocycte-derived dendritic cells, eosinophils, and neutrophils, as well as on mature spermatozoa and epithelial cells lining the male genital tract. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 \/ CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gly25-Ser36\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 30.2 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38-50 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43113995174067,"sku":"PKSH033863-20","price":478.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43113995206835,"sku":"PKSH033863-100","price":1293.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e3a0eccd-132c-4f85-a788-ca6f7462dbec.png?v=1709549920","url":"https:\/\/afsbio.com\/products\/recombinant-human-cd52-c-fc-avi-biotinylated-pksh033863","provider":"AFSBio Inc.","version":"1.0","type":"link"}