{"product_id":"recombinant-human-cd72-lyb-2-protein-trx-his-pksh032112","title":"Recombinant Human CD72\/Lyb-2 Protein (Trx\u0026His) - PKSH032112","description":"\u003cp\u003eRecombinant Human CD72\/Lyb-2 Protein (Trx\u0026amp;His)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032112-10, PKSH032112-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD72; Lyb-2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: B-Cell Differentiation Antigen CD72; Lyb-2; CD72\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P21854\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-Trx-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P21854\u003c\/p\u003e\n\n\u003cp\u003eBackground: B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6\/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Arg117-Cys226\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 30.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 14\u0026amp;17\u0026amp;32 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43083657281715,"sku":"PKSH032112-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43083657314483,"sku":"PKSH032112-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_21b62968-768f-4f6f-95db-048c5fd241d1.png?v=1708946391","url":"https:\/\/afsbio.com\/products\/recombinant-human-cd72-lyb-2-protein-trx-his-pksh032112","provider":"AFSBio Inc.","version":"1.0","type":"link"}