{"product_id":"recombinant-human-cd8-beta-cd8b-protein-his-tag-pksh033383","title":"Recombinant Human CD8 beta\/CD8B Protein (His Tag) - PKSH033383","description":"\u003cp\u003eRecombinant Human CD8 beta\/CD8B Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033383-10, PKSH033383-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD8 beta; CD8B\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: T-Cell Surface Glycoprotein CD8 Beta Chain; CD8b; CD8B; CD8B1; LEU2; LY3; LYT3; P37\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P10966\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P10966-1\u003c\/p\u003e\n\n\u003cp\u003eBackground: T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen; acting as a coreceptor; and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains; or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene; also located on chromosome 2; has been identified.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu22-Pro170\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 17.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 29 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43149124337843,"sku":"PKSH033383-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43149124370611,"sku":"PKSH033383-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_40aa914e-00fd-4f4e-ac26-aa7d3d263e4f.png?v=1710341046","url":"https:\/\/afsbio.com\/products\/recombinant-human-cd8-beta-cd8b-protein-his-tag-pksh033383","provider":"AFSBio Inc.","version":"1.0","type":"link"}