{"product_id":"recombinant-human-cdo-cdon-protein-his-tag-pksh033720","title":"Recombinant Human CDO\/CDON Protein (His Tag) - PKSH033720","description":"\u003cp\u003eRecombinant Human CDO\/CDON Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH033720-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CDO; CDON\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Cell adhesion molecule-related\/down-regulated by oncogenes; CDON; CDO\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: epigenetics and nuclear signal; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q4KMG0\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q4KMG0\u003c\/p\u003e\n\n\u003cp\u003eBackground: CDO (CAMrelated\/down-regulatedby oncogenes) is a member of the Immunoglubulin (Ig) superfamily, Ig\/Fibronectin (FN)type III repeat family of cell surface proteins. Human CDO is a type I transmembrane (TM) glycoprotein. It is synthesized as a 1287 amino acid (aa) precursorthat contains a 25 aa signal sequence, a 938 aa extracellular domain (ECD), a 21 aa TM segment and a 303 aa cytoplasmic region. The ECD contains five C2-typeIglikedomains, followed by three FN type III repeats. The ECD of human CDO is 85% aa identical to mouse CDO ECD.CDO is found on muscle precursor and neural progenitor cells of the embryo. It likely promotes muscle differentiation, and contributes to axon guidance andneuronal patterning.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Asp26-Pro943\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 85 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 100.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 120-135 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104253051059,"sku":"PKSH033720-50","price":366.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_26153d8c-c8a2-42ef-b233-139ecde11185.png?v=1709293009","url":"https:\/\/afsbio.com\/products\/recombinant-human-cdo-cdon-protein-his-tag-pksh033720","provider":"AFSBio Inc.","version":"1.0","type":"link"}