{"product_id":"recombinant-human-ceacam5-cd66e-cea-c-6his-avi-biotinylated-pksh033864","title":"Recombinant Human CEACAM5\/CD66e\/CEA (C-6His-Avi) Biotinylated - PKSH033864","description":"\u003cp\u003eRecombinant Human CEACAM5\/CD66e\/CEA (C-6His-Avi) Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033864-20, PKSH033864-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CEACAM5; CD66e; CEA\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e; CEACAM5\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Tags \u0026amp; Cell Markers; Microbiology; Cancer; immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His-Avi\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P06731\u003c\/p\u003e\n\n\u003cp\u003eAccession: P06731\u003c\/p\u003e\n\n\u003cp\u003eBackground: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Lys35-Ala685\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 74.2 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 110-150 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43113995272371,"sku":"PKSH033864-20","price":478.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43113995305139,"sku":"PKSH033864-100","price":1293.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_bbea9909-fe76-4576-af14-db232bfbda2c.png?v=1709549924","url":"https:\/\/afsbio.com\/products\/recombinant-human-ceacam5-cd66e-cea-c-6his-avi-biotinylated-pksh033864","provider":"AFSBio Inc.","version":"1.0","type":"link"}