{"product_id":"recombinant-human-cfhr1-protein-his-tag-pdeh100161","title":"Recombinant Human CFHR1 protein (His tag) - PDEH100161","description":"\u003cp\u003eRecombinant Human CFHR1 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEH100161-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CFHR1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Complement Factor H-Related Protein 1; FHR-1; H Factor-Like Protein 1; H-Factor-Like 1; H36; CFHR1; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q03591\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q03591\u003c\/p\u003e\n\n\u003cp\u003eBackground: Complement Factor H-Related 1 (CFHR1) is a 43 kDa secreted member of the factor H family of glycoproteins. The human Complement Factor H protein family consists of the complement and immune regulators factor H; the factor H-like protein 1 (FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains; termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids in length. It contains five; approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation; lipid metabolism and lipoprotein complexes that bind PMNs to LPS.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Thr205-Lys329\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 13.64 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43072324108467,"sku":"PDEH100161-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3143399e-4b8f-4fe0-8eb5-c65ca9a7df18.png?v=1708685539","url":"https:\/\/afsbio.com\/products\/recombinant-human-cfhr1-protein-his-tag-pdeh100161","provider":"AFSBio Inc.","version":"1.0","type":"link"}