{"product_id":"recombinant-human-chl-1-protein-his-tagactive-pksh031836","title":"Recombinant Human CHL-1 Protein (His Tag)(Active) - PKSH031836","description":"Recombinant Human CHL-1 Protein (His Tag)(Active)\n\nSize: 50μg\n\nCatalogue Number: PKSH031836-50\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: CHL-1\n\nTarget Symptom: CALL; L1CAM2; LICAM2\n\nTarget Species: Human\n\nExpression Host: HEK293 Cells\n\nApplication: Cell culture; ELISA\n\nFusion Tag: C-His\n\nAccession: AAI04919.1\n\nBackground: Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF \/ NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsive transcription factor and is considered as a member of the largest ctf complementation group, consisting of 30 of 126 ctf mutants isolated. CHL1 is a cell adhesion molecule highly related to L1. It contains structure plan of six extracellular C2-type immunoglobulin (Ig) domains followed by five fibronectin typeⅢ domains linked by a single membrane-spanning region to a short cytoplasmic domain. The extracellular portion of CHL1 is higyly glycosylated and involved them in hemophilic disease.\n\nActivity: Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. When 5 x 10\u003csup\u003e4\u003c\/sup\u003e cells\/well are added to CHL1 coated plates (0.8 μg\/ml and 100 μl\/well), approximately 40%-60% will adhere specifically after 60 minutes at 37℃.\n\nSequence: Met 1-Gln 1080\n\nPurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 7.4\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\n\nCalculated MW: 120 kDa\n\nObserved MW: 160-180 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104260194483,"sku":"PKSH031836-50","price":1024.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5a3b2393-1e14-4b4f-9873-8ad7a8134157.png?v=1709293243","url":"https:\/\/afsbio.com\/products\/recombinant-human-chl-1-protein-his-tagactive-pksh031836","provider":"AFSBio Inc.","version":"1.0","type":"link"}