{"product_id":"recombinant-human-clec4e-mincel-protein-his-tag-pksh032258","title":"Recombinant Human CLEC4E\/Mincel Protein (His Tag) - PKSH032258","description":"\u003cp\u003eRecombinant Human CLEC4E\/Mincel Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032258-10, PKSH032258-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CLEC4E; Mincel\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: C-Type Lectin Domain Family 4 Member E; C-Type Lectin Superfamily Member 9; Macrophage-Inducible C-Type Lectin; CLEC4E; CLECSF9; MINCLE\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9ULY5\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9ULY5\u003c\/p\u003e\n\n\u003cp\u003eBackground: C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C\/EBP β and is thought to play a role in the inflammatory response, possibly via transcriptional control of C\/EBP β. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional control of CEBPB. Human CLEC4E shares 67% sequence identity with its mouse counterpart, suggesting a similar function between species. CLEC-4E exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to a natural killer gene complex region on human chromosome 12.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Arg41-Leu219\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 21.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 26 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43092751286451,"sku":"PKSH032258-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43092751319219,"sku":"PKSH032258-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3b721b30-a81f-4a2d-91d3-ea512d3edb7a.png?v=1709119361","url":"https:\/\/afsbio.com\/products\/recombinant-human-clec4e-mincel-protein-his-tag-pksh032258","provider":"AFSBio Inc.","version":"1.0","type":"link"}