{"product_id":"recombinant-human-collectin-11-colec11-protein-his-tag-pksh032268","title":"Recombinant Human Collectin-11\/COLEC11 Protein (His Tag) - PKSH032268","description":"\u003cp\u003eRecombinant Human Collectin-11\/COLEC11 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032268-10, PKSH032268-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Collectin-11; COLEC11\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Collectin-11; Collectin Kidney Protein 1; CL-K1; COLEC11\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9BWP8\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9BWP8\u003c\/p\u003e\n\n\u003cp\u003eBackground: Collectin-11 is a secreted protein that belongs to the COLEC10\/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS). It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2).\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gln26-Met271\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27.1 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 30 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43092752957619,"sku":"PKSH032268-10","price":155.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43092752990387,"sku":"PKSH032268-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e8a16266-a164-41c6-abcb-3cb750bd3d5a.png?v=1709119383","url":"https:\/\/afsbio.com\/products\/recombinant-human-collectin-11-colec11-protein-his-tag-pksh032268","provider":"AFSBio Inc.","version":"1.0","type":"link"}