{"product_id":"recombinant-human-cradd-raidd-protein-pksh033738","title":"Recombinant Human CRADD\/RAIDD Protein - PKSH033738","description":"\u003cp\u003eRecombinant Human CRADD\/RAIDD Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033738-10, PKSH033738-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CRADD; RAIDD\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Death Domain-Containing Protein CRADD; Caspase and RIP Adapter with Death Domain; RIP-Associated Protein with A Death Domain; CRADD; RAIDD\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cell biology; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: None\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P78560\u003c\/p\u003e\n\n\u003cp\u003eAccession: P78560\u003c\/p\u003e\n\n\u003cp\u003eBackground: Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues; with particularly high expression in the adult heart; testis; liver; skeletal muscle; fetal liver; and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2; and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL\/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis\/cell death in numerous tissues. Defects in CRADD will result in mental retardation.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Glu199\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 23 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 21 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113985802419,"sku":"PKSH033738-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113985835187,"sku":"PKSH033738-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4832999b-1f23-48f1-9491-4dfbec94effe.png?v=1709549707","url":"https:\/\/afsbio.com\/products\/recombinant-human-cradd-raidd-protein-pksh033738","provider":"AFSBio Inc.","version":"1.0","type":"link"}