{"product_id":"recombinant-human-ctgf-ccn2-protein-fc-tag-pksh032276","title":"Recombinant Human CTGF\/CCN2 Protein (Fc Tag) - PKSH032276","description":"\u003cp\u003eRecombinant Human CTGF\/CCN2 Protein (Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032276-10, PKSH032276-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CTGF; CCN2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; CTGF; IGFBP8\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P29279\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: P29279\u003c\/p\u003e\n\n\u003cp\u003eBackground: CTGF belongs to the CCN (CTGF\/Cyr61\/Cef10\/NOVH) protein family; which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT); a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gln27-Ala349\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 62.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 88 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43092754858163,"sku":"PKSH032276-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43092754890931,"sku":"PKSH032276-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7ecda6ad-4982-423a-a768-30bfd9a3a2f7.png?v=1709119405","url":"https:\/\/afsbio.com\/products\/recombinant-human-ctgf-ccn2-protein-fc-tag-pksh032276","provider":"AFSBio Inc.","version":"1.0","type":"link"}