{"product_id":"recombinant-human-ctnnb1-protein-pdeh100082","title":"Recombinant Human CTNNB1 Protein - PDEH100082","description":"\u003cp\u003eRecombinant Human CTNNB1 Protein\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEH100082-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CTNNB1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Catenin beta-1; Beta-catenin; CTNNB; OK; SW-cl.35; PRO2286\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P35222\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Neuroscience; Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P35222\u003c\/p\u003e\n\n\u003cp\u003eBackground: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met131-Tyr670\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 85 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 59 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 59 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43072321257651,"sku":"PDEH100082-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_828cd8bd-8ff0-4115-9b29-500fd4045b0d.png?v=1708685414","url":"https:\/\/afsbio.com\/products\/recombinant-human-ctnnb1-protein-pdeh100082","provider":"AFSBio Inc.","version":"1.0","type":"link"}