{"product_id":"recombinant-human-cxcl12-24-88-proteinn-hisactive-pksh034169","title":"Recombinant Human CXCL12 (24-88) protein(N-His)(active) - PKSH034169","description":"\u003cp\u003eRecombinant Human CXCL12 (24-88) protein(N-His)(active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH034169-20, PKSH034169-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CXCL12\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: Cell culture\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P48061\u003c\/p\u003e\n\n\u003cp\u003eAccession: P48061\u003c\/p\u003e\n\n\u003cp\u003eBackground: Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1α and SDF1β are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface; and can also bind syndecan4. SDF1 is known to influence lymphopoiesis; regulate patterning and cell number of neural progenitors; and promote angiogenesis. It also enhances the survival of myeloid progenitor cells.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measure by its ability to chemoattract BaF3 cells transfected with human CXCR4. The ED50 for this effect is \u0026lt; 0.5 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSequence: MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 98 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a solution containing 20 mM sodium citrate, 0.1 MNaCl, pH 4.5.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 11.49 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43118172897459,"sku":"PKSH034169-20","price":348.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43118172930227,"sku":"PKSH034169-100","price":1034.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2ede5453-5ad0-4a45-ac76-2673614dbcd7.png?v=1709637498","url":"https:\/\/afsbio.com\/products\/recombinant-human-cxcl12-24-88-proteinn-hisactive-pksh034169","provider":"AFSBio Inc.","version":"1.0","type":"link"}