{"product_id":"recombinant-human-cyclophilin-a-protein-his-tag-pksh031608","title":"Recombinant Human Cyclophilin A Protein (His Tag) - PKSH031608","description":"\u003cp\u003eRecombinant Human Cyclophilin A Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH031608-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Cyclophilin A\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Peptidyl-prolyl cis-trans isomerase A; PPIase A; Cyclophilin A; Cyclosporin A-binding protein; Rotamase A; SP18; PPIA; CYPA\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P62937\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; immunology;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P62937\u003c\/p\u003e\n\n\u003cp\u003eBackground: Peptidyl-prolyl cis-trans isomerase A; also known as PPIase A; Rotamase A; Cyclophilin A; Cyclosporin A-binding protein; PPIA and CYPA; is a cytoplasm protein which belongs to thecyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity; suggesting that they influence the conformation of proteins in cells. PPIA \/ Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA \/ Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli; and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA \/ Cyclophilin A can interact with several HIV proteins; including p55 gag; Vpr; and capsid protein; and has been shown to be necessary for the formation of infectious HIV virions.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Glu 165\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 97 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile 50mM Tris, 150mM NaCl, 20% glycerol, pH 7.7\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 19.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 19 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083647910067,"sku":"PKSH031608-100","price":1127.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_43da079d-36bd-4505-90e4-119d18ef4746.png?v=1708946139","url":"https:\/\/afsbio.com\/products\/recombinant-human-cyclophilin-a-protein-his-tag-pksh031608","provider":"AFSBio Inc.","version":"1.0","type":"link"}