{"product_id":"recombinant-human-cyclophilin-b-ppib-protein-his-tag-pksh033569","title":"Recombinant Human Cyclophilin B\/PPIB Protein (His Tag) - PKSH033569","description":"\u003cp\u003eRecombinant Human Cyclophilin B\/PPIB Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033569-10, PKSH033569-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Cyclophilin B; PPIB\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: CYP-S1; CYPB; HEL-S-39; OI9; SCYLP\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; immunology; Isotypeloading control;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P23284\u003c\/p\u003e\n\n\u003cp\u003eAccession: P23284\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis\/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Asp34-Ala212\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 20.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 21 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113970172083,"sku":"PKSH033569-10","price":155.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113970204851,"sku":"PKSH033569-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_cc71c87a-9380-41fe-ac32-d725de9231f8.png?v=1709549386","url":"https:\/\/afsbio.com\/products\/recombinant-human-cyclophilin-b-ppib-protein-his-tag-pksh033569","provider":"AFSBio Inc.","version":"1.0","type":"link"}