{"product_id":"recombinant-human-cystatin-d-cst5-protein-rp01035","title":"Recombinant Human Cystatin-D\/CST5 Protein - RP01035","description":"\u003cp\u003eRecombinant Human Cystatin-D\/CST5 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01035-10, RP01035-20, RP01035-50, RP01035-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Cystatin-D\/CST5 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly21-Val142) of human Cystatin D (Accession #NP_001891.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CST5, MGC71922, CST5\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P28325\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1473\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. As a member of type 2 cystatin, cystatin D is a single-domain protein and also has cysteine residues that form disulfide bridges. The functions of Cystatin D are largely unknown. However, Cystatin D has been shown to inhibit coronavirus replication at its physiological concentration (0.12_x005f\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate Z-FR-AM. The IC50 value is \u0026lt;18 nM.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: GSASAQSRTLAGGIHATDLNDKSVQCALDFAISEYNKVINKDEYYSRPLQVMAAYQQIVGGVNYYFNVKFGRTTCTKSQPNLDNCPFNDQPKLKEEEFCSFQINEVPWEDKISILNYKCRKV\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198315356339,"sku":"RP01035-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198315389107,"sku":"RP01035-20","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198315421875,"sku":"RP01035-50","price":490.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198315454643,"sku":"RP01035-100","price":784.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_03bfffdb-5fe2-4620-88f8-0dfa2e2d4f59.png?v=1766960510","url":"https:\/\/afsbio.com\/products\/recombinant-human-cystatin-d-cst5-protein-rp01035","provider":"AFSBio Inc.","version":"1.0","type":"link"}