{"product_id":"recombinant-human-dcxr-protein-his-tag-pksh032714","title":"Recombinant Human DCXR Protein (His Tag) - PKSH032714","description":"\u003cp\u003eRecombinant Human DCXR Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032714-10, PKSH032714-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: DCXR\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: L-Xylulose Reductase; XR; Carbonyl Reductase II; Dicarbonyl\/L-Xylulose Reductase; Kidney Dicarbonyl Reductase; kiDCR; Sperm Surface Protein P34H; DCXR\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q7Z4W1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q7Z4W1\u003c\/p\u003e\n\n\u003cp\u003eBackground: L-Xylulose Reductase is an enzyme that belongs to the Short-Chain Dehydrogenases\/Reductases (SDR) family. L-Xylulose Reductase is responsible for the metabolism of Xylulose, converting it into Xylitol. L-Xylulose Reductase catalyzes the NADPH-dependent reduction of several Pentoses, Tetroses, Trioses, α-Dicarbonyl compounds and L-Xylulose. L-Xylulose Reductase participates in the Uronate Cycle of Glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing Xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Cys244\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 1mM DTT, 30% Glycerol, 1mM DTT, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28.1 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 29 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068882550963,"sku":"PKSH032714-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068882583731,"sku":"PKSH032714-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b06ef7f9-72b9-4c56-92d0-fc61e13d449c.png?v=1708598506","url":"https:\/\/afsbio.com\/products\/recombinant-human-dcxr-protein-his-tag-pksh032714","provider":"AFSBio Inc.","version":"1.0","type":"link"}