{"product_id":"recombinant-human-decorin-pg-s2-dcn-protein-rp02157","title":"Recombinant Human Decorin\/PG-S2\/DCN Protein - RP02157","description":"\u003cp\u003eRecombinant Human Decorin\/PG-S2\/DCN Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP02157-10, RP02157-20, RP02157-50, RP02157-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Decorin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp31-Lys359) of human Decorin (Accession #P07585) fused with a hFC tag at the C- terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: DCN, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B, decorin, Decorin\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P07585\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1634\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Decorin is a secreted chondroitin\/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). SLRP family members are characterized by N-terminal and C-terminal cysteine-rich regions which flank the central region containing 10-12 tandem leucine-rich repeats (LRR). The human Decorin cDNA encodes a 359 amino acid (aa) precursor that includes a 16 aa signal sequence and a 14 aa propeptide. Alternate splicing of human Decorin generates five isoforms with variable length deletions. Decorin is an N-glycosylated protein that also carries a variablysized hybrid chondroitin\/dermatan sulfate chain at Ser34. Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors FGF2,GDF8\/Myostatin, TGFβ,and WISP1. It also binds and activates EGF R, ErbB4, and IGFI-R. In vivo, Decorin promotes myoblast differentiation, supports angiogenesis, and inhibits tumor progression.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFC\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: DEASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198273314995,"sku":"RP02157-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198273347763,"sku":"RP02157-20","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198273380531,"sku":"RP02157-50","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198273413299,"sku":"RP02157-100","price":336.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_4d11b669-10aa-4541-8701-6a85b3c83ffc.png?v=1766959981","url":"https:\/\/afsbio.com\/products\/recombinant-human-decorin-pg-s2-dcn-protein-rp02157","provider":"AFSBio Inc.","version":"1.0","type":"link"}