{"product_id":"recombinant-human-ephrin-a3-efna3-protein-rp01714","title":"Recombinant human Ephrin-A3\/EFNA3 Protein - RP01714","description":"\u003cp\u003eRecombinant human Ephrin-A3\/EFNA3 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01714-10, RP01714-20, RP01714-50, RP01714-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant human Ephrin-A3\/EFNA3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met 1-Ser 213) of human Ephrin-A3\/EFNA3 (Accession #NP_004943.1.) fused with and a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: EFL2; EPLG3; LERK3; Ehk1-L; EFNA3\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P52797-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1944\u003c\/p\u003e\n\n\u003cp\u003eSpecies: human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ephrin-A3 (Ephrin A3) is also known as EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, EFL2, EPLG3 and LERK3,which comprises the largest subfamily of receptor protein-tyrosine kinases (RTKs), and has been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis. Ephrin A3 is cell surface GPI-bound ligand for Eph receptors and belongs to the family of receptor tyrosine kinases. Ephrin can bind promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human EFNA3(Catalog: RP01714) at 2 μg\/mL (100 μL\/well) can bind Human EphA3 (Catalog: RP00186) with a linear range of 0.02-2.82 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MAAAPLLLLLLLVPVPLLPLLAQGPGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQGFKRWECNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSIS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198333280435,"sku":"RP01714-10","price":140.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198333313203,"sku":"RP01714-20","price":154.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198333345971,"sku":"RP01714-50","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198333378739,"sku":"RP01714-100","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_553c6672-15ff-487e-95c6-00ef4a90aee3.png?v=1766960706","url":"https:\/\/afsbio.com\/products\/recombinant-human-ephrin-a3-efna3-protein-rp01714","provider":"AFSBio Inc.","version":"1.0","type":"link"}