{"product_id":"recombinant-human-ephrin-a5-efna5-protein-his-tag-pdmh100084","title":"Recombinant Human Ephrin-A5\/EFNA5 protein (His tag) - PDMH100084","description":"\u003cp\u003eRecombinant Human Ephrin-A5\/EFNA5 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDMH100084-20, PDMH100084-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Ephrin-A5; EFNA5\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Ephrin-A5; EPLG7; LERK7; EFNA5; LERK-7; EPH-related receptor tyrosine kinase ligand 7; AL-1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P52803\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Neuroscience;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P52803\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ephrin-A5 (EFNA5) belongs to the ephrin family, contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate\/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Asn203\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 32.67 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 32 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43083618975923,"sku":"PDMH100084-20","price":264.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43083619008691,"sku":"PDMH100084-100","price":418.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_ac27d6b5-ae6d-4460-9281-4f8d3fcd907c.png?v=1708945347","url":"https:\/\/afsbio.com\/products\/recombinant-human-ephrin-a5-efna5-protein-his-tag-pdmh100084","provider":"AFSBio Inc.","version":"1.0","type":"link"}