{"product_id":"recombinant-human-fbpase-1-fbp1-protein-human-cells-his-tag-pksh033277","title":"Recombinant Human FBPase 1\/FBP1 Protein (Human Cells, His Tag) - PKSH033277","description":"\u003cp\u003eRecombinant Human FBPase 1\/FBP1 Protein (Human Cells, His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033277-10, PKSH033277-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: FBPase 1; FBP1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Fructose-1; 6-bisphosphatase 1; D-fructose-1; 6-bisphosphate 1-phosphohydrolase 1; FBP; FBPase 1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Cancer; epigenetics and nuclear signal; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P09467\u003c\/p\u003e\n\n\u003cp\u003eAccession: P09467\u003c\/p\u003e\n\n\u003cp\u003eBackground: Fructose-1; 6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1; 6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala2-Gln338\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 37.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113940451507,"sku":"PKSH033277-10","price":343.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113940484275,"sku":"PKSH033277-50","price":576.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_92cceb9d-f702-435c-bd57-3ae5b00a8f35.png?v=1709548989","url":"https:\/\/afsbio.com\/products\/recombinant-human-fbpase-1-fbp1-protein-human-cells-his-tag-pksh033277","provider":"AFSBio Inc.","version":"1.0","type":"link"}