{"product_id":"recombinant-human-fgl1-c-avi-6his-biotinylated-pksh033856","title":"Recombinant Human FGL1 (C-Avi-6His) Biotinylated - PKSH033856","description":"\u003cp\u003eRecombinant Human FGL1 (C-Avi-6His) Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033856-20, PKSH033856-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: FGL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Avi-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q08830\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q08830\u003c\/p\u003e\n\n\u003cp\u003eBackground: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Human LAG-3-Fc at 10μg\/ml (100 μl\/well) can bind Biotinylated Human FGL1-Avi. The ED50 of Human FGL1-Avi is 1908ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu23-Ile312\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 36.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43118161559731,"sku":"PKSH033856-20","price":546.0,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43118161592499,"sku":"PKSH033856-100","price":1372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_59c760f7-44ca-4ffb-9291-63fc27c62f76.png?v=1709637337","url":"https:\/\/afsbio.com\/products\/recombinant-human-fgl1-c-avi-6his-biotinylated-pksh033856","provider":"AFSBio Inc.","version":"1.0","type":"link"}