{"product_id":"recombinant-human-fgl1-c-fc-pksh033854","title":"Recombinant Human FGL1 (C-Fc) - PKSH033854","description":"\u003cp\u003eRecombinant Human FGL1 (C-Fc)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033854-10, PKSH033854-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: FGL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q08830\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q08830\u003c\/p\u003e\n\n\u003cp\u003eBackground: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Cynomolgus LAG-3-His at 2μg\/ml (100 μl\/well) can bind Human FGL1-Fc. The ED50 of Human FGL1-Fc is 5. 8 ug\/ml.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu23-Ile312\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 60.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 55-65 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43118161330355,"sku":"PKSH033854-10","price":184.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43118161363123,"sku":"PKSH033854-50","price":550.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_96039464-abce-4b54-960f-e0dd663f7d74.png?v=1709637329","url":"https:\/\/afsbio.com\/products\/recombinant-human-fgl1-c-fc-pksh033854","provider":"AFSBio Inc.","version":"1.0","type":"link"}