{"product_id":"recombinant-human-fkbp1a-fkbp12-protein-rp00051","title":"Recombinant Human FKBP1A\/FKBP12 Protein - RP00051","description":"\u003cp\u003eRecombinant Human FKBP1A\/FKBP12 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20ug, 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00051-10, RP00051-20, RP00051-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human FKBP1A\/FKBP12 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Glu108) of human FKBP12 (Accession #NP_000792.1).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE, FKBP1A, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P62942\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2280\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198363394227,"sku":"RP00051-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198363426995,"sku":"RP00051-20","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198363459763,"sku":"RP00051-50","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_9c6d3b65-1522-4728-97ec-565b337e238d.png?v=1766961214","url":"https:\/\/afsbio.com\/products\/recombinant-human-fkbp1a-fkbp12-protein-rp00051","provider":"AFSBio Inc.","version":"1.0","type":"link"}