{"product_id":"recombinant-human-fkbp4-c-6his-ept273","title":"Recombinant Human FKBP4 (C-6His) - EPT273","description":"\u003cp\u003eRecombinant Human FKBP4 (C-6His)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: EPT273-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT\/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.\u003c\/p\u003e \n\n\u003cp\u003eAlternate Names: Peptidyl-prolyl cis-trans isomerase FKBP4; 51kDa FK506-binding protein; 51kDa FK506-binding protein; 59kDa immunophilin; FK506-binding protein 4; FKBP59; HSP-binding immunophilin; immunophilin FKBP52; Rotamase; FKBP4\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human 52 kDa FK506 Binding Protein is produced by our E.coli expression system and the target gene encoding Met1-Ala459 is expressed with a 6His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q02790\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 52.8 KDa\u003c\/p\u003e\n\n\u003cp\u003eApparent Molecular Weight: 50-60 KDa, reducing conditions\u003c\/p\u003e\n\n\u003cp\u003eStorage Condition: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003ePurity: Greater than 95% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 0.1 ng\/µg (1 EU\/µg) as determined by LAL test.\u003c\/p\u003e\n\n\u003cp\u003eDelivery Condition: The product is shipped on dry ice\/polar packs. Upon receipt, store it immediately at the temperature listed below.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"Default Title","offer_id":43211051172019,"sku":"EPT273-50","price":278.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_46e602c5-dd3f-41ea-b3bb-1a58a2cebdce.png?v=1767117561","url":"https:\/\/afsbio.com\/products\/recombinant-human-fkbp4-c-6his-ept273","provider":"AFSBio Inc.","version":"1.0","type":"link"}