{"product_id":"recombinant-human-fkbp4-protein-his-tag-pksh032877","title":"Recombinant Human FKBP4 Protein (His Tag) - PKSH032877","description":"\u003cp\u003eRecombinant Human FKBP4 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032877-10, PKSH032877-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: FKBP4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Peptidyl-prolyl cis-trans isomerase FKBP4; 51kDa FK506-binding protein; 51kDa FK506-binding protein; 59kDa immunophilin; FK506-binding protein 4; FKBP59; HSP-binding immunophilin; immunophilin FKBP52; Rotamase; FKBP4\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q02790\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; epigenetics and nuclear signal;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q02790\u003c\/p\u003e\n\n\u003cp\u003eBackground: FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT\/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Ala459\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 10%glycerol, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 52.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 58 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068753379507,"sku":"PKSH032877-10","price":284.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068753412275,"sku":"PKSH032877-50","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3ec77a56-32f0-4b3d-8508-b8d95fe47e93.png?v=1708597360","url":"https:\/\/afsbio.com\/products\/recombinant-human-fkbp4-protein-his-tag-pksh032877","provider":"AFSBio Inc.","version":"1.0","type":"link"}