{"product_id":"recombinant-human-galectin-9-lgals9-protein-his-tagactive-pksh032470","title":"Recombinant Human Galectin 9\/LGALS9 Protein (His Tag)(Active) - PKSH032470","description":"\u003cp\u003eRecombinant Human Galectin 9\/LGALS9 Protein (His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032470-10, PKSH032470-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Galectin 9; LGALS9\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21; LGALS9\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q3B8N1\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q3B8N1-2\u003c\/p\u003e\n\n\u003cp\u003eBackground: Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2\/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Human Galectin 9-His at 10μg\/ml(100 μl\/well) can bind Cynomolgus TIM-3-His(Cat: PKSQ050023). The ED50 of Human Galectin 9-His is 1.75 ug\/ml.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Thr323\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, 1mM EDTA, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 36.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 49 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43114028073139,"sku":"PKSH032470-10","price":155.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43114028105907,"sku":"PKSH032470-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5a40bbe7-73b2-4ccd-9d6b-8412971131f3.png?v=1709550463","url":"https:\/\/afsbio.com\/products\/recombinant-human-galectin-9-lgals9-protein-his-tagactive-pksh032470","provider":"AFSBio Inc.","version":"1.0","type":"link"}