{"product_id":"recombinant-human-galectin-9-proteinn-hisactive-pksh034185","title":"Recombinant Human Galectin-9 protein(N-His)(active) - PKSH034185","description":"Recombinant Human Galectin-9 protein(N-His)(active)\n\nSizes: 20μg, 100μg\n\nCatalogue Numbers: PKSH034185-20, PKSH034185-100\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: Galectin-9\n\nTarget Symptom: LGALS9; HUATA; LGALS9\n\nTarget Species: Human\n\nExpression Host: E.coli\n\nApplication: Cell culture; ELISA\n\nFusion Tag: N-His\n\nUNIProt ID: A0A024QZ02\n\nAccession: A0A024QZ02\n\nBackground: Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin' s disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2\/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.\n\nActivity: Measured by its ability of the immobilized protein to support the adhesion of Jurkat cells. The ED50 for this effect is \u0026lt; 3 μg\/mL.\n\nSequence: MAFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT\n\nPurity: \u0026gt; 98 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 7.4\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: \u0026lt; 0.1 EU per μg of the protein as determined by the LAL method.\n\nCalculated MW: 36.72 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43118173782195,"sku":"PKSH034185-20","price":348.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43118173814963,"sku":"PKSH034185-100","price":1034.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_aa27c9b0-0ce1-4bd3-a4db-bc9e8ecbeb8f.png?v=1709637516","url":"https:\/\/afsbio.com\/products\/recombinant-human-galectin-9-proteinn-hisactive-pksh034185","provider":"AFSBio Inc.","version":"1.0","type":"link"}