{"product_id":"recombinant-human-gapdh-protein-rp00775","title":"Recombinant Human GAPDH Protein - RP00775","description":"\u003cp\u003eRecombinant Human GAPDH Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: RP00775-50, RP00775-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human GAPDH Protein is produced by E. coli system. The target protein is expressed with sequence (Gly2-Glu335) of Human GAPDH(Accession #P04406) fused with No Tag.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: GAPDH, GAPD, CDABP0047, OK\/SW-cl.12\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P04406\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2597\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: GAPDH is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: NO-Tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: GKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"50ug","offer_id":45198359920819,"sku":"RP00775-50","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198359953587,"sku":"RP00775-100","price":336.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_5e6edb26-e84a-4e41-b781-eeb15a1ad449.png?v=1766961151","url":"https:\/\/afsbio.com\/products\/recombinant-human-gapdh-protein-rp00775","provider":"AFSBio Inc.","version":"1.0","type":"link"}