{"product_id":"recombinant-human-gba3-cbgl1-protein-his-tagactive-pksh031073","title":"Recombinant Human GBA3\/CBGL1 Protein (His Tag)(Active) - PKSH031073","description":"\u003cp\u003eRecombinant Human GBA3\/CBGL1 Protein (His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH031073-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GBA3; CBGL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: CBG; CBGL1; GBA3; GLUC; KLrP; MGC104276; MGC126878\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: Baculovirus-Insect Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: Enzyme\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: NP_066024.1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 \/ CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 \/ CBGL1 is present in small intestine (at protein level). GBA3 \/ CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 \/ CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 \/ CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 \/ CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measured by its ability to hydrolyze 4-methylumbelliferyl-β-D glucopyranoside. The specific activity is \u0026gt; 1, 500 pmoles\/min\/μg.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Leu 469\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 7.4\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 55 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104294240435,"sku":"PKSH031073-50","price":1213.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_cbc18777-f067-4b44-b496-de2f30777a59.png?v=1709293874","url":"https:\/\/afsbio.com\/products\/recombinant-human-gba3-cbgl1-protein-his-tagactive-pksh031073","provider":"AFSBio Inc.","version":"1.0","type":"link"}