{"product_id":"recombinant-human-gmpr-protein-human-cells-his-tag-pksh033290","title":"Recombinant Human GMPR Protein (Human Cells, His Tag) - PKSH033290","description":"\u003cp\u003eRecombinant Human GMPR Protein (Human Cells, His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033290-10, PKSH033290-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GMPR\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: GMP Reductase 1; Guanosine 5'-Monophosphate Oxidoreductase 1; Guanosine Monophosphate Reductase 1; GMPR; GMPR1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Cell biology;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P36959\u003c\/p\u003e\n\n\u003cp\u003eAccession: P36959\u003c\/p\u003e\n\n\u003cp\u003eBackground: GMP Reductase 1 (GMPR) is a member of the IMPDH\/GMPR family. GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase; nucleoside and nucleotide derivatives of G to A nucleotides; and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Ser345\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 40% glycerol, 0.15M NaCl and 1mM DTT, pH8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 38.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113943072947,"sku":"PKSH033290-10","price":385.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113943105715,"sku":"PKSH033290-50","price":735.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6f85dc41-f5af-4633-8cc4-044463180ee7.png?v=1709549005","url":"https:\/\/afsbio.com\/products\/recombinant-human-gmpr-protein-human-cells-his-tag-pksh033290","provider":"AFSBio Inc.","version":"1.0","type":"link"}