{"product_id":"recombinant-human-hai-2-spint2-protein-his-tag-pksh033658","title":"Recombinant Human HAI-2\/SPINT2 Protein (His Tag) - PKSH033658","description":"\u003cp\u003eRecombinant Human HAI-2\/SPINT2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033658-10, PKSH033658-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HAI-2; SPINT2\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Kunitz-Type Protease Inhibitor 2; Hepatocyte Growth Factor Activator Inhibitor Type 2; HAI-2; Placental Bikunin; SPINT2; HAI2; KOP\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cell biology; Neuroscience; Developmental Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O43291\u003c\/p\u003e\n\n\u003cp\u003eAccession: O43291\u003c\/p\u003e\n\n\u003cp\u003eBackground: Hepatocyte Growth Factor Activator Inhibitor Type 2 (HAI2) is a single-pass type I membrane protein and contains two BPTI\/Kunitz inhibitor domains. The first Kunitz domain is mainly responsible for the inhibitory activity against hepatocyte growth factor activator (HGFA). HAI2 is expressed in placenta, kidney, pancreas, prostate, testis, thymus and trachea. HAI2 serves as a inhibitor of HGF activator. It also inhibits plasmin, plasma and tissue kallikrein and factor XIa. Defects in HAI2 are the cause of diarrhea type 3 (DIAR3), also known as congenital sodium diarrhea (CSD).\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala28-Lys197\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 20.22 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 24-30 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113980002483,"sku":"PKSH033658-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113980068019,"sku":"PKSH033658-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3cce6d7e-a0fd-47cb-ace2-2ae61330214d.png?v=1709549559","url":"https:\/\/afsbio.com\/products\/recombinant-human-hai-2-spint2-protein-his-tag-pksh033658","provider":"AFSBio Inc.","version":"1.0","type":"link"}