{"product_id":"recombinant-human-hepcidin-hamp-protein-gst-tag-pksh032540","title":"Recombinant Human Hepcidin\/HAMP Protein (GST Tag) - PKSH032540","description":"\u003cp\u003eRecombinant Human Hepcidin\/HAMP Protein (GST Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032540-10, PKSH032540-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Hepcidin; HAMP\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor; HEPC; LEAP1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P81172\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cardiovascular; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-GST\u003c\/p\u003e\n\n\u003cp\u003eAccession: P81172\u003c\/p\u003e\n\n\u003cp\u003eBackground: Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Asp60-Thr84\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 85 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of PBS, 50%glycerol, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 29.2 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 28-30 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068848799923,"sku":"PKSH032540-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068848832691,"sku":"PKSH032540-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_ae8c14be-8bba-440b-ac14-2f8b4b396d02.png?v=1708598178","url":"https:\/\/afsbio.com\/products\/recombinant-human-hepcidin-hamp-protein-gst-tag-pksh032540","provider":"AFSBio Inc.","version":"1.0","type":"link"}