{"product_id":"recombinant-human-hla-a-0201-ny-eso-1-complex-protein-c-10his-pksh034036","title":"Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His) - PKSH034036","description":"\u003cp\u003eRecombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH034036-10, PKSH034036-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HLA-A*0201 NY-ESO-1 complex\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: MHC; MY-ESO-1; HLA-A*0201 NY-ESO-1 complex Protein\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Microbiology; immunology; Cardiovascular; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-10His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P61769\u0026amp;P01892\u003c\/p\u003e\n\n\u003cp\u003eAccession: P61769\u0026amp;P01892\u003c\/p\u003e\n\n\u003cp\u003eBackground: NY-ESO-1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. Optimally assembled peptide-HLA-B2M trimer translocates to the surface of antigen-presenting cells, where it interacts with TCR and CD8 coreceptor on the surface of T cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: SLLMWITQC\u0026amp;Ile21-Met119\u0026amp;Gly25-Ile308(Ala269Val)\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 49.1 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 55-60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43114016080051,"sku":"PKSH034036-10","price":217.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43114016112819,"sku":"PKSH034036-50","price":646.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a795ec92-33c6-4f56-8a92-7a06507560ce.png?v=1709550233","url":"https:\/\/afsbio.com\/products\/recombinant-human-hla-a-0201-ny-eso-1-complex-protein-c-10his-pksh034036","provider":"AFSBio Inc.","version":"1.0","type":"link"}