{"product_id":"recombinant-human-ifn-alpha-2-protein-rp01432","title":"Recombinant Human IFN-alpha 2 Protein - RP01432","description":"\u003cp\u003eRecombinant Human IFN-alpha 2 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01432-10, RP01432-20, RP01432-50, RP01432-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IFN-alpha 2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Glu188) of human Interferon alpha 2\/IFNA2 (Accession #NP_000596.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2, interferon alpha-2, Interferon alpha 2 (IFN-α2) , IFN-alphaA, IFNA, IFNA2B, INFA2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P01563\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3440\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: 1.Measured by its binding ability in a functional ELISA.Immobilized Human IFNA2 at 2 μg\/mL (100 μL\/well) can bind Human IFNAR2 with a linear range of 0.2-617ng\/mL.|2.Recombinant human IFN-α2 (10 ng\/mL) was used to treat HCT116 cells. Western-blot result showed that both the level of phosphorylated STAT1 and STAT3 were increased, indicating the stimulation was successful.(Customer Feedback Data)\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: CDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198319321267,"sku":"RP01432-10","price":140.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198319354035,"sku":"RP01432-20","price":154.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198319386803,"sku":"RP01432-50","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198319419571,"sku":"RP01432-100","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_e45a181f-2991-4e24-b580-6b0400903dbe.png?v=1766960554","url":"https:\/\/afsbio.com\/products\/recombinant-human-ifn-alpha-2-protein-rp01432","provider":"AFSBio Inc.","version":"1.0","type":"link"}