{"product_id":"recombinant-human-ifngr1-protein-his-tag-pksh033429","title":"Recombinant Human IFNGR1 Protein (His Tag) - PKSH033429","description":"\u003cp\u003eRecombinant Human IFNGR1 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033429-10, PKSH033429-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IFNGR1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: CD119; IFNGR; IMD27A; IMD27B; Interferon gamma receptor 1; IFNGR1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Microbiology; immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P15260\u003c\/p\u003e\n\n\u003cp\u003eAccession: P15260\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser\/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Glu18-Ser245\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40-50 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113957851315,"sku":"PKSH033429-10","price":292.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113957884083,"sku":"PKSH033429-50","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_467672df-a5f9-4d28-bf15-5f4d463d0e83.png?v=1709549180","url":"https:\/\/afsbio.com\/products\/recombinant-human-ifngr1-protein-his-tag-pksh033429","provider":"AFSBio Inc.","version":"1.0","type":"link"}