{"product_id":"recombinant-human-igf2bp2-protein-rp02186","title":"Recombinant Human IGF2BP2 Protein - RP02186","description":"\u003cp\u003eRecombinant Human IGF2BP2 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: RP02186-10, RP02186-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IGF2BP2 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Met1-Thr220) of human IGF2BP-2 (Accession #Q9Y6M1) fused with a T7 tag at the N-terminus and a 6xHis tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IGF2BP2, IMP-2, IMP2, VICKZ2, IMP2, VICKZ2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9Y6M1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10644\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 80 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP\/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: N-T7\u0026amp;C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198351499443,"sku":"RP02186-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198351532211,"sku":"RP02186-50","price":630.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_cbfacc34-9f07-4aa3-a218-bc7b0c260e76.png?v=1766960942","url":"https:\/\/afsbio.com\/products\/recombinant-human-igf2bp2-protein-rp02186","provider":"AFSBio Inc.","version":"1.0","type":"link"}