{"product_id":"recombinant-human-igfbp3-proteinhis-tag-pdmh100044","title":"Recombinant Human IGFBP3 protein(His tag) - PDMH100044","description":"\u003cp\u003eRecombinant Human IGFBP3 protein(His tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDMH100044-20, PDMH100044-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IGFBP3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: IBP-3; IGF-binding protein 3; IGFBP-3\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P17936\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P17936\u003c\/p\u003e\n\n\u003cp\u003eBackground: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219\/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity.Promotes testicular germ cell apoptosis.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Lys291\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 80 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 32.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38-42 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43149104709811,"sku":"PDMH100044-20","price":264.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43149104742579,"sku":"PDMH100044-100","price":418.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_525d84ec-0fdc-43e3-94ee-ef892ac8159d.png?v=1710340729","url":"https:\/\/afsbio.com\/products\/recombinant-human-igfbp3-proteinhis-tag-pdmh100044","provider":"AFSBio Inc.","version":"1.0","type":"link"}