{"product_id":"recombinant-human-ikb-alpha-nfkbia-protein-rp00032","title":"Recombinant Human IkB-alpha\/NFKBIA Protein - RP00032","description":"\u003cp\u003eRecombinant Human IkB-alpha\/NFKBIA Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00032-10, RP00032-20, RP00032-50, RP00032-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IkB-alpha\/NFKBIA Protein is produced by E. coli expression system. The target protein is expressed with sequence (Phe2-Leu317) of human IkB-alpha (Accession #NP_065390.1).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IKBA, MAD-3, NFKBI, NFKBIA, MAD-3, NFKBI, IKB alpha, EDAID2, IKBA, NFKB inhibitor alpha\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P25963\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4792\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein is a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The protein is interacts with REL dimers to inhibit NF-kappa-B\/REL complexes which are involved in inflammatory responses. The protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IkB-alpha Protein at 2 μg\/mL (100 μL\/well) can bind IκBα Rabbit mAb with a linear range of 0.195-0.64 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: FQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198293729459,"sku":"RP00032-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198293762227,"sku":"RP00032-20","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198293794995,"sku":"RP00032-50","price":490.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198293827763,"sku":"RP00032-100","price":784.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_7539ad8b-75be-4219-a0f8-1d00ac5fac71.png?v=1766960231","url":"https:\/\/afsbio.com\/products\/recombinant-human-ikb-alpha-nfkbia-protein-rp00032","provider":"AFSBio Inc.","version":"1.0","type":"link"}