{"product_id":"recombinant-human-il-1-alpha-protein-rp03505","title":"Recombinant Human IL-1 alpha Protein - RP03505","description":"\u003cp\u003eRecombinant Human IL-1 alpha Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP03505-10, RP03505-20, RP03505-50, RP03505-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IL-1 alpha Protein is produced by E. coli Cells system. The target protein is expressed with sequence (Ser113-Ala271) of Human IL-1 alpha (Accession #NP_000566.3) fused with No tag.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IL1A, IL1F1,  Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P01583\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3552\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is 9.39-37.58 pg\/mL, corresponding to a specific activity of 2.66×10^7~1.06×10^8 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: NO-Tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: SAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198343110835,"sku":"RP03505-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198343143603,"sku":"RP03505-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198343176371,"sku":"RP03505-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198343209139,"sku":"RP03505-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_0d6f1a48-c6b8-4ae1-9a18-dd418bc0f021.png?v=1766960825","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-1-alpha-protein-rp03505","provider":"AFSBio Inc.","version":"1.0","type":"link"}