{"product_id":"recombinant-human-il-16-protein-rp00038","title":"Recombinant Human IL-16 Protein - RP00038","description":"\u003cp\u003eRecombinant Human IL-16 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00038-10, RP00038-20, RP00038-50, RP00038-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IL-16 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Pro2-Ser130) of human IL-16 (Accession #NP_757366.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IL16, LCF, NIL16, PRIL16, prIL-16\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q14005\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3603\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The biological activities ascribed to IL-16 are reported to be dependent on the cell surface expression of CD4, suggesting that IL-16 is a CD4 ligand. Besides its chemotactic properties, IL-16 has also been shown to suppress HIV-1 replication in vitro. Recombinant E. coli-derived IL-16 produced at is present mostly as a monomer, exhibits chemotactic activity for lymphocytes at high concentrations, lacks chemotactic activites for monocytes, and binds the extracellular domain of CD4 with low affinity.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant human IL16 at 5 μg\/mL (100 μL\/well) can bind Recombinant human CD4 with a linear range of 0.2-1 μg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: PDLNSSTDSAASASAASDVSVESTAEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198294646963,"sku":"RP00038-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198294679731,"sku":"RP00038-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198294712499,"sku":"RP00038-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198294745267,"sku":"RP00038-100","price":672.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_e59e2564-b65a-4846-8308-9350099c3a36.png?v=1766960241","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-16-protein-rp00038","provider":"AFSBio Inc.","version":"1.0","type":"link"}