{"product_id":"recombinant-human-il-17c-protein-rp02709","title":"Recombinant Human IL-17C Protein - RP02709","description":"\u003cp\u003eRecombinant Human IL-17C Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP02709-10, RP02709-20, RP02709-50, RP02709-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IL-17C Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (His19-Val197) of Human IL-17C (Accession #NP_037410.1) fused with a His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CX2; Cytokine CX2; IL17C; IL-17C; IL-17CMGC126884\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9P0M4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 27189\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin 17C (IL-17C) is a 15-20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL-17 cytokines (IL?17A?F) are encoded by separate genes but adopt a conserved cystine knot fold. IL?17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198226882739,"sku":"RP02709-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198226915507,"sku":"RP02709-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198226948275,"sku":"RP02709-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198226981043,"sku":"RP02709-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_976766fa-f462-40a5-b3e0-a17ab55095bb.png?v=1766959446","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-17c-protein-rp02709","provider":"AFSBio Inc.","version":"1.0","type":"link"}