{"product_id":"recombinant-human-il-18r1-cd218a-protein-rp00097","title":"Recombinant Human IL-18R1\/CD218a Protein - RP00097","description":"\u003cp\u003eRecombinant Human IL-18R1\/CD218a Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00097-10, RP00097-20, RP00097-50, RP00097-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IL-18R1\/CD218a Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu20-Arg329) of human IL18R1\/CD218a (Accession #NP_003846.1) fused with an Fc, 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP, IL18R1\/IL-18 R alpha\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q13478\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8809\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 85 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1\/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA.Immobilized IL18R1 Mouse mAb at 1μg\/mL (100 μL\/well) can bind Human IL18R1 with a linear range of 0.03-1.06ng\/ml.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u0026amp;His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: ESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198295859379,"sku":"RP00097-10","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198295892147,"sku":"RP00097-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198295924915,"sku":"RP00097-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198295957683,"sku":"RP00097-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_7a905034-f5f4-44b9-a9fa-c188c2fa85ea.png?v=1766960260","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-18r1-cd218a-protein-rp00097","provider":"AFSBio Inc.","version":"1.0","type":"link"}