{"product_id":"recombinant-human-il-1r8-il1rapl1-protein-aa-19-357-his-tag-pksh033634","title":"Recombinant Human IL-1R8\/IL1RAPL1 Protein (aa 19-357, His Tag) - PKSH033634","description":"\u003cp\u003eRecombinant Human IL-1R8\/IL1RAPL1 Protein (aa 19-357, His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033634-10, PKSH033634-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL-1R8; IL1RAPL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Interleukin-1 Receptor Accessory Protein-Like 1; IL-1-RAPL-1; IL-1RAPL-1; IL1RAPL-1; Oligophrenin-4; Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2; TIGIRR-2; X-Linked Interleukin-1 Receptor Accessory Protein-Like 1; IL1RAPL1; OPHN4\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9NZN1\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9NZN1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin-1 receptor accessory protein-like 1; also known as IL1RAPL1; can be detected at low levels in heart; skeletal muscle; ovary; skin; amygdala; caudate nucleus; corpus callosum; hippocampus; substantia nigra and thalamus. IL1RAPL1 functions as a homodimer; it interacts with NCS1; PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation; it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Leu19-Thr357\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 40 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50-70 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113977905331,"sku":"PKSH033634-10","price":354.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113977970867,"sku":"PKSH033634-50","price":1061.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_212fc619-0e59-41a2-b249-02d86400cb2f.png?v=1709549514","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-1r8-il1rapl1-protein-aa-19-357-his-tag-pksh033634","provider":"AFSBio Inc.","version":"1.0","type":"link"}