{"product_id":"recombinant-human-il-2-receptor-subunit-beta-il-2rb-cd122-c-6his-avi-biotinylated-pksh033917","title":"Recombinant Human IL-2 Receptor Subunit Beta\/IL-2RB\/CD122 (C-6His-Avi) Biotinylated - PKSH033917","description":"\u003cp\u003eRecombinant Human IL-2 Receptor Subunit Beta\/IL-2RB\/CD122 (C-6His-Avi) Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033917-20, PKSH033917-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL-2RB; CD122\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Interleukin-2 receptor subunit beta; IL2RB; IL-2 receptor subunit beta; IL-2R subunit beta; High affinity IL-2 receptor subunit beta; CD122\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Biotinylated\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His-Avi\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P14784\u003c\/p\u003e\n\n\u003cp\u003eAccession: P14784\u003c\/p\u003e\n\n\u003cp\u003eBackground: Human IL-2RB, also known asinterleukin-2 receptor subunit beta, is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein, and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala27-Asp239\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35-45 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43113999171763,"sku":"PKSH033917-20","price":478.8,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43113999204531,"sku":"PKSH033917-100","price":1293.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8121e2e3-c010-4f92-a3e5-35c9c46f806e.png?v=1709550011","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-2-receptor-subunit-beta-il-2rb-cd122-c-6his-avi-biotinylated-pksh033917","provider":"AFSBio Inc.","version":"1.0","type":"link"}