{"product_id":"recombinant-human-il-23-il-12b-il-23a-protein-rp01160","title":"Recombinant Human IL-23\/IL-12B\u0026IL-23A Protein - RP01160","description":"\u003cp\u003eRecombinant Human IL-23\/IL-12B\u0026amp;IL-23A Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01160-10, RP01160-20, RP01160-50, RP01160-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Active Recombinant Human IL-12B\u0026amp;IL-23A Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ile23-Ser328\u0026amp;Arg20-Pro189) of human IL-23 (Accession #NP_002178.2\/NP_057668.1) fused with a 6×His tag at the N-terminus(IL23A).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IL-23 p19\/IL-12 p40, IL23, SGRF , IL-23 alpha \u0026amp; IL-12 beta\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P29460\u0026amp;Q9NPF7\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3593\u0026amp;51561\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: 1.Measured by its binding ability in a functional ELISA.Immobilized Human IL-12B\u0026amp;IL-23A at 5μg\/mL (100 μL\/well) can bind Human IL23R with a linear range of 4-135 ng\/ml.|2.Measured by its ability to induce IL-17 secretion by mouse splenocytes. The ED50 for this effect is 21.23-84.94 ng\/mL, corresponding to a specific activity of 1.17×10^4 ~4.71×10^4 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag(IL12B)\u0026amp;N-his(IL23A)\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: IWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWASVPCS\/\/RAVPGGSSPAWTQCQQLSQKLCTLAWSAHPLVGHMDLREEGDEETTNDVPHIQCGDGCDPQGLRDNSQFCLQRIHQGLIFYEKLLGSDIFTGEPSLLPDSPVGQLHASLLGLSQLLQPEGHHWETQQIPSLSPSQPWQRLLLRFKILRSLQAFVAVAARVFAHGAATLSP\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198285570227,"sku":"RP01160-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198285602995,"sku":"RP01160-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198285635763,"sku":"RP01160-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198285668531,"sku":"RP01160-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_2f2dee7e-a9c6-418a-904a-4bdbb92acd2d.png?v=1766960136","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-23-il-12b-il-23a-protein-rp01160","provider":"AFSBio Inc.","version":"1.0","type":"link"}