{"product_id":"recombinant-human-il-2ra-cd25-protein-rp01405","title":"Recombinant Human IL-2RA\/CD25 Protein - RP01405","description":"\u003cp\u003eRecombinant Human IL-2RA\/CD25 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01405-10, RP01405-20, RP01405-50, RP01405-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human IL-2RA\/CD25 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu22-Cys213) of human CD25\/IL-2Ralpha (Accession #NP_000408.1) fused with a Fc, 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IL2RA, CD25, IDDM10, IL2R, IMD41, TCGFR, p55, interleukin-2 receptor subunit alpha, CD25, IDDM10, IL2R, IMD41, TCGFR, p55\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P01589\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3559\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized human IL2 (Catalog: RP01039) at 2 μg\/ml (100 μL\/well) can bind human IL2RA with a linear range of 0.01-396.60 ng\/mL\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u0026amp;His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: ELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSC\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198325350579,"sku":"RP01405-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198325383347,"sku":"RP01405-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198325416115,"sku":"RP01405-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198325448883,"sku":"RP01405-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_3eaf0bb5-37e2-4f9f-986e-5a37fac006d9.png?v=1766960625","url":"https:\/\/afsbio.com\/products\/recombinant-human-il-2ra-cd25-protein-rp01405","provider":"AFSBio Inc.","version":"1.0","type":"link"}